研究成果

实验室在精神疾病与精神卫生学领域取得一系列成果，近年来，承担省级课题29项，市级和其他课题18项，涉及精神障碍流行病学调查（涉及普通人群精神障碍患病率调查、睡眠障碍患病率调查、早年应激相关精神障碍调查等）、精神障碍发病机制研究（涉及遗传学、神经影像学、生物标记物、动物模型、认知功能、机器学习等多学科方向）、精神障碍创新诊疗手段（涉及非药物治疗手段、睡眠监测、中药治疗等）的探讨；发表SCI论文6篇，科研获奖10余项。其中，多巴胺受体D2型与超高危及首发精神分裂症人群的相关性研究荣获保定市科技进步奖一等奖；首发双相I型障碍躁狂发作患者的随访研究荣获保定市科技进步奖二等奖；巴戟天寡糖胶囊联合舍曲林治疗抑郁症的临床研究荣获保定市科技进步奖二等奖等。

主要论文成果

1. Sun L, Li K, Zhang L, Zhang Y. Associations Between Self-Reported Sleep Disturbances and Cognitive Impairment: A Population-Based Cross-Sectional Study. Nat Sci Sleep. 2022 Feb 15;14:207-216. doi: 10.2147/NSS.S347658. PMID: 35210888; PMCID: PMC8857964.

2. Sun L, Li K, Zhang Y, Zhang L. Differentiating the associations between sleep quality and suicide behaviors: A population-based study in China. J Affect Disord. 2022 Jan 15;297:553-558. doi: 10.1016/j.jad.2021.10.126. Epub 2021 Oct 30. PMID: 34728292.

3. Sun L, Li K, Zhang Y, Zhang L. Sleep-related healthcare use prevalence among adults with insomnia symptoms in Hebei, China: a population-based cross-sectional study. BMJ Open. 2022 Aug 17;12(8):e057331. doi: 10.1136/bmjopen-2021-057331. PMID: 35977764; PMCID: PMC9389099.

4. Zhang YS, Rao WW, Zhang LL, Jia HX, Bi H, Wang HL, Balbuena L, Li KQ, Xiang YT. Incidence rate of schizophrenia after the Tangshan earthquake in China: a 44-year retrospective birth cohort study. Transl Psychiatry. 2022 Sep 6;12(1):365. doi: 10.1038/s41398-022-02125-3. PMID: 36068195; PMCID: PMC9448782.

5. Yang J, Fan J, Cheng A, Zhao W, Wu D, Cui W, Zhang Y, Liu X. Hemodynamic analysis of the frontal cortex using multi-task fNIRS in major depressive disorder. J Affect Disord. 2022 Oct 15;315:206-212. doi: 10.1016/j.jad.2022.08.001. Epub 2022 Aug 4. PMID: 35932939.

6. Wen M, Dong Z, Zhang L, Li B, Zhang Y, Li K. Depression and Cognitive Impairment: Current Understanding of Its Neurobiology and Diagnosis. Neuropsychiatr Dis Treat. 2022 Nov 29;18:2783-2794. doi: 10.2147/NDT.S383093. PMID: 36471744; PMCID: PMC9719265.

7. 刘力慧,李斯妮,程奥博等.抑郁症患者自杀与血脂等因素相关性[J].中国健康心理学杂志,2022,30(06):820-825.

8. 王艳华,贾海玲,毕皓等.河北省老年人认知功能与睡眠质量关联分析[J].中国神经精神疾病杂志,2022,48(02):96-100.

9. 蔡淑君,史文佳,徐涛等.新冠肺炎治愈者的心理健康及睡眠质量状况调查[J].中国心理卫生杂志,2022,36(06):539-544.